CLINICAL PRACTICE GUIDELINES FOR MANAGEMENT OF RECURRENT APHTHOUS STOMATITIS

Abstract

Recurrent aphthous stomatitis (RAS) is one of the most commonly seen oral mucosal disease which is characterized by presence of multiple recurrent, round or ovoid ulcers known as aphthae or canker sores, which have circumscribed margins, erythematous haloes, and yellow or grey floors. The fundamental goals of treatment are to shorten the duration of ulcer, provide relief from pain & increase disease-free periods while the secondary goals would be
to lessen the frequency & severity of recurrences. Even though several treatment modalities have been recommended, only a few are evidence based and can be considered for the optimal management of RAS. The objective of this study was to propose and review treatment protocol to be followed for the optimal management of RAS. We reviewed several evidence-based studies and through this review we recommend topical interventions as the first-line of treatment since they are associated with low risk of systemic side effects. Due to limitations in the number of evidence-based studies, larger evidence-based clinical trials and literature reviews are needed to further improve the optimal protocol for the effective management of RAS.