ANTIFUNGAL EFFECT OF LACTOBACILLUS ACIDOPHILUS CRUDE EXTRACT

Abstract

This study were carried out to investigate the effect of   Lactobacillusacidophilus crude extract which produce  many active compounds such as organic acids, polyols, exopolysaccharides and antimicrobial compounds,( which have several applications in the food industry) on two types of fungi, including Candida albicans , which is isolated from some pregnant women in teaching  Bahgdad hospital / Iraq with chronicurinary tract infection, and Trichophyton rubrum which is isolated from the central public health laboratory  from patients who contracted skin infections. After isolating the fungus diagnosed by phenotypiclly and microscopically to adopt in the current study.  The results showed the strong effect of the bacterial secretions against all the fungi adopted in this study, through the emergence of large inhibition areas in the cultivars planted with fungus after comparing them the size of the mold or yeast under controlling as reached the largest inhibition zone as 25.0 ± 1.7 for to Trichophyton rubrum, while the inhibition was complete for C. albicans .

Keywords:Lactobacillus acidophilus, dermatophytic fungus, Candida albicans , urinary tract infection.